Executive Leadership Team

Board of Directors

Arie Belldegrun, M.D.

Arie Belldegrun, M.D.

Chairman

Dr. Belldegrun is the Chairman of UroGen Pharma and has served as our Chair since December 2012. He has built a distinguished career as a visionary surgeon, scientist, and life sciences entrepreneur.

Dr. Belldegrun founded Kite Pharma, a biopharmaceutical company engaged in the development of innovative cancer immunotherapies, where he served as Chairman, President, and Chief Executive Officer until the acquisition of Kite by Gilead Sciences in October 2017.

Dr. Belldegrun has had a distinguished tenure in the life sciences and has been closely involved with the founding and advancement of several successful biopharmaceutical companies, including Cougar Biotechnology and Agensys. Abiraterone, developed by Cougar, is a mainstay of therapy for patients with metastatic prostate cancer.

Dr. Belldegrun most recently co-founded Allogene Therapeutics, a clinical stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (CAR T) therapies for cancer. He serves as Executive Chairman of Allogene; Chairman of Two River Group and Kronos Bio; Co-Founder and Senior Managing Director of Vida Ventures, a life science venture group.

Dr. Belldegrun is a Professor of Urology, holds the Roy and Carol Doumani Chair in Urologic Oncology, and is Director of the UCLA Institute of Urologic Oncology at the David Geffen School of Medicine at UCLA.

Prior to joining UCLA, Dr. Belldegrun served as a research fellow in surgical oncology and immunotherapy under Dr. Steven A. Rosenberg at the National Cancer Institute/NIH. He completed his M.D. at the Hebrew University Hadassah Medical School in Jerusalem, Israel, his post-graduate studies in immunology at the Weizmann Institute of Science, Israel, and his residency in urologic surgery at Harvard Medical School. He has authored several books on oncology and more than 500 scientific and medical papers related to urological cancers, immunotherapy, gene therapy, and cancer vaccines. Dr. Belldegrun is certified by the American Board of Urology and is a fellow of the American Association of Genitourinary Surgeons.

Liz Barrett

Liz Barrett

President and Chief Executive Officer

Ms. Barrett is a highly regarded industry leader with extensive experience leading business organizations and Fortune 500 pharmaceutical companies.

Ms. Barrett has served as director and our President and Chief Executive Officer since January 2019. Prior to UroGen, Ms. Barrett was CEO of Novartis Oncology and a member of the Novartis Executive Committee since February 2018.

Prior to Novartis, Ms. Barrett served at Pfizer, Inc. in various leadership capacities, most recently as the Global President of Oncology and, before that, as President of Global Innovative Pharma for Europe, President of the Specialty Care Business Unit for North America, and Regional President of United States Oncology.

Before Pfizer, Ms. Barrett held positions at Cephalon, Inc., where she was Vice President and General Manager of the Oncology Business Unit, and at Johnson & Johnson. She started her career at Kraft Foods Group, Inc.

Ms. Barrett also currently serves on the boards of directors of Sage Therapeutics and Allogene Therapeutics.

Ms. Barrett received an M.B.A. degree in marketing from Saint Joseph's University and a B.S. from the University of Louisiana.

Cynthia Butitta

Cynthia Butitta

Board Member

Ms. Butitta is a seasoned financial and operational executive with more than 25 years of leadership experience in both the biotechnology and high-technology industries. She has served as a director for UroGen since October 2017.

Most recently, Ms. Butitta served as Chief Operating Officer of Kite Pharma, where she played an instrumental role in the acquisition of Kite Pharma by Gilead Sciences for approximately $11.9 billion in cash. She also served as Kite Pharma’s Executive Vice President and Chief Financial Officer from 2014 to 2016. During her tenure at Kite, Ms. Butitta was responsible for securing more than $1 billion in equity financing and oversaw the rapid growth of the organization.

Prior to joining Kite, Ms. Butitta served as Senior Vice President and Chief Financial Officer of NextWave Pharmaceuticals, Inc., which was acquired in 2012 by Pfizer, Inc. for $700 million.

Previously, Ms. Butitta held positions as Chief Operating Officer and Chief Financial Officer of Telik Inc., a public biotechnology company focused on the development of small molecule drugs for the treatment of cancer, prior to its acquisition by MabVax Therapeutics, Inc.

Ms. Butitta was also Vice President of Finance and Administration and Chief Financial Officer for Connetics, Inc., a public biotechnology company.

Ms. Butitta also serves on the boards of Autolus Ltd. since March 2018, Olema Oncology since August 2020, and Century Therapeutics since February 2021.

Ms. Butitta received a B.S. degree with honors in business and accounting from Edgewood College in Madison, Wisconsin, and her M.B.A. degree in finance from the University of Wisconsin, Madison.

Fred E. Cohen, M.D.

Fred E. Cohen, M.D.

Board Member

Dr. Cohen is a former academic clinician with many years of experience advising pharmaceutical and life sciences companies. Dr. Cohen has served as a director for UroGen since May 2017.

Dr. Cohen is a Senior Advisor to TPG Capital, where he served for more than 15 years as a Partner, and founder of TPG Biotechnology, a life science-focused venture capital fund.

Beginning in November 2017, Dr. Cohen has served as a co-founder and senior managing director of Vida Ventures, LLC, a biotechnology venture capital fund.

In addition, for more than two decades throughout his career, Dr. Cohen has been affiliated with the University of California, San Francisco, where he has held various clinical positions, including as a research scientist, an internist for hospitalized patients, a consulting endocrinologist, and the Chief of the Division of Endocrinology and Metabolism.

Dr. Cohen also currently serves on the board of directors of Progyny, CareDx, and Intellia Therapeutics.

Dr. Cohen received his B.S. degree in molecular biophysics and biochemistry from Yale University, his D.Phil. in molecular biophysics from Oxford on a Rhodes Scholarship, and his M.D. from Stanford. He is a member of the National Academy of Medicine and the American Academy of Arts and Sciences.

Dr. Cohen currently serves on the board of directors of several other biotechnology and pharmaceutical companies.

Stuart Holden, M.D.

Stuart Holden, M.D.

Board Member

Dr. Holden has a long and decorated career as a practicing urologist, research pioneer in prostate and urologic cancers, and an academic. He has served as a director for UroGen since December 2015.

Dr. Holden has been the Chairman of ProQuest Investments’ Scientific Advisory Board since its founding in 1998.

Since 2014, Dr. Holden has held a number of positions within the Department of Urology at the David Geffen School of Medicine at UCLA, including Health Sciences Clinical Professor of Urology, Spielberg Family Chair in Urologic Oncology, and Associate Director of the UCLA Institute of Urologic Oncology.

Dr. Holden has worked on the front lines of prostate cancer for more than 36 years and has pioneered new treatments for urologic cancers. Dr. Holden’s dedication to patient care resulted in him being named Medical Director of the Prostate Cancer Foundation, the world’s largest funding organization of prostate cancer research; he has held this position since the foundation’s inception in 1993.

Dr. Holden previously held a position as the director of the Louis Warschaw Prostate Cancer Center at Cedars-Sinai Medical Center and was the first holder of the Warschaw, Robertson, Law Families Chair in Prostate Cancer.

Dr. Holden was also a founding partner of Tower Urology in Los Angeles and also currently serves on the board of directors of Clarus Therapeutics.

Dr. Holden completed his medical degree and received his surgical training at Weill Cornell Medical College and the New York Hospital-Cornell University Medical College. He completed his urology residency at Emory University School of Medicine and fellowships in urology and developmental genetics at Memorial Sloan-Kettering Cancer Center. He was also awarded a clinical fellowship from the American Cancer Society and received a B.S. degree from the University of Wisconsin-Madison.

Ran Nussbaum

Ran Nussbaum

Board Member

Mr. Nussbaum is a successful entrepreneur and executive with deep expertise in the business of the pharmaceutical industry. His work revolves around constant and active involvement in companies, providing them with strategic and business development oversight. He has served as a director for UroGen since May 2013.

Mr. Nussbaum is a Managing Partner and co-founder of Pontifax Group, which has established seven funds with over one billion dollars under management and invested in over 100 portfolio companies around the globe. The group has established more than 19 startups since it was incorporated in 2005.

In the past, Mr. Nussbaum served on the board of directors for Kite Pharma (sold to Gilead), ArQule (sold to Merck) and cCEM Therapeutics (sold to Merck). He has also chaired Ocon Medical and NasVax Therapeutics and was CEO at Spearhead Ltd. and Biomedix Ltd.

Currently, Mr. Nussbaum also sits on the board of Eloxx (ELOX), Prevail (PRVL), and Lutris. He also serves as Keros Therapeutics’ Chairman of the Board.

Leana S. Wen, M.D., M.Sc.

Leana S. Wen, M.D., M.Sc.

Board Member

Dr. Wen is an emergency physician and has served as a professor of health policy and management at the George Washington University School of Public Health since September 2019. She has been a contributing columnist for The Washington Post since June 2020, writing on health policy and public health, and an on-air commentator for CNN as a medical analyst since August 2020. From January 2015 to October 2018, she was the health commissioner for the city of Baltimore, where she led the nation’s oldest continuously operating health department to combat the opioid epidemic and improve maternal and child health. From 2013 to 2015, Dr. Wen served as director of patient-centered care research in the department of emergency medicine at George Washington University and authored a critically acclaimed book on patient advocacy. She is currently on the board of the Bipartisan Policy Center, Baltimore Community Foundation, and National Committee on U.S.-China Relations, and chairs the advisory board of the Behavioral Health Group. She has also been a global health fellow at the World Health Organization, a consultant with the China Medical Board, and a nonresident senior fellow at the Brookings Institution. Dr. Wen also served as the President of Planned Parenthood from 2018 through 2019.

She has been a member of more than 10 nonprofit boards, including serving as the chair of Behavioral Health System Baltimore. Dr. Wen has also served on the board of directors of Glaukos Corporation since March 2021 and also serves on its audit committee. Dr. Wen’s work has been recognized by numerous professional organizations, including as one of Modern Healthcare's Top 50 Physician-Executives and a member of the Council on Foreign Relations. In 2019, she was named one of TIME magazine’s 100 Most Influential People and in 2022 as one of Modern Healthcare's 100 Most Influential People in Healthcare. She holds a B.S. from California State University, Los Angeles, an M.D. from Washington University School of Medicine, and two M.Sc.s from the University of Oxford, where she was a Rhodes Scholar. She completed her residency training at Brigham & Women’s Hospital and Massachusetts General Hospital, where she was a clinical fellow at Harvard Medical School.