Innovative technology for transformative treatment
We're pioneering bold new possibilities for patients living with specialty cancers and urologic diseases. Our novel technological advances are breaking down barriers in treatment and building up radically new standards of care.
Together we can transform local therapies—in urology and beyond
RTGel™ reverse-thermal hydrogel technology is transforming medicine delivery in urology
When confronted with challenging conditions in urology, too often there’s no right tool for the job.
That’s why UroGen has developed RTGel, an innovative technology platform designed to work with anatomical complexity—not against it—and facilitate intracavitary treatment of challenging urological conditions.
The safety and effectiveness of UroGen’s investigational product candidates that utilize RTGel technology have not been established. For illustrative purposes only.
Experience RTGel™ Technology
Experience RTGel™ Technology
Dynamic, reverse-thermal properties
RTGel is an innovative hydrogel that possesses dynamic, reverse-thermal properties—it exists as a liquid at lower temperatures and converts to gel form at body temperature.
Instilled as a chilled liquid
RTGel is designed to be formulated with an active drug and instilled directly into a target organ as a chilled liquid.Instillation under chilled conditions promotes ease of delivery and conformation to the organ’s specific anatomy
Extended dwell time as a gel
As the temperature of the formulation rises to body temperature, it converts to gel form.The formulation is then intended to dwell in the target organ for several hours while providing sustained exposure of active drug.
Excreted via normal urine flow
RTGel is gradually liquified and excreted via normal urine flow. It does not block or interfere with the flow of urine.
Therapeutic possibilities
The RTGel platform has the potential to advance the treatment of urological conditions by:
Increasing dwell time and exposure of active drugs, potentially improving the therapeutic effects of existing products
Potentially increasing the viability of organ-sparing techniques and providing alternatives to radical surgery