Immunotherapy for the Treatment of Urothelial Carcinoma

The Journal of Urology; January 2017; Volume 197, Issue 1, Pages 14–22 Donin NM1, Lenis AT1, Holden S1, Drakaki A1, Pantuck A1, Belldegrun A1, Chamie K2. 1 Department of Urology, Institute of Urologic Oncology, David Geffen School of Medicine at UCLA, Los … Continue reading

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Serial retrograde instillations of sustained release formulation of mitomycin C to the upper urinary tract of the Yorkshire swine using a thermosensitive polymer: Safety and feasibility

Urol Oncol. 2017 Jan 3. Donin NM1, Strauss-Ayali D2, Agmon-Gerstein Y2, Malchi N2, Lenis AT3, Holden S3, Pantuck AJ4, Belldegrun AS4, Chamie K4. 1Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, CA. 2UroGen Pharma Ltd., … Continue reading

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The Chemoablative Effect of VesiGel® Instillation in Patients with NMIBC – Preliminary Results

SUO poster presentation, Thursday, Dec 1, 2016 Andrew T. Lenis1, Karim Chamie1, Boris Friedman2, Andrea Tubaro3, Ami Sidi4, Daniel Kedar5, Lorenzo Colombo6, Dov Engelstein7, Joan Palau8, Gregory Wirth9, Ilan Leibovitch10, Eddy Fridman11, Ifat Klein12, Michal Jeshurun12, Fred Witjes13 1Department of Urology, … Continue reading

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Thermo Reversible Hydrogel Base Delivery of Mitomycin C (MitoGel®) for Treatment of Upper Tract Urothelial Carcinoma (UTUC)

SUO poster presentation, Thursday, Dec 1, 2016 Jeffery Lin BS1, Nir Kleinmann MD2, Gregory Wirth MD3, Surena Matin MD4, Ofer Nativ MD5, Gil Mayer MD5, Fred Witjes MD6, Asaf Shvero MD2, Karim Chamie MD7, Allen Pantuck MD8, Angie Smith MD9, Mark … Continue reading

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Sustained-release Formulation of Mitomycin C to the Upper Urinary Tract Using a Thermosensitive Polymer: A Preclinical Study

Urology. 2016 Oct 5. pii: S0090-4295(16)30689-6. doi: 0.1016/j.urology.2016.09.039. [Epub ahead of print] Donin NM1, Duarte S2, Lenis AT3, Caliliw R3, Torres C2, Smithson A2, Strauss-Ayali D4, Agmon-Gerstein Y4, Malchi N4, Said J5, Raman SS6, Holden S3, Pantuck A7, Belldegrun AS7, … Continue reading

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A phase 2 study of TMX-101, intravesical imiquimod, for the treatment of carcinoma in situ bladder cancer

Journal of Urologic Oncology, 2016 Nicholas M. Donin, Karim Chamie, Andrew T. Lenis, Allan J. Pantuck, Madhu Reddy, Dana Kivlin, Johanna Holldack, Rafaella Pozzi, and others Highlights •TMX-101 0.4% is a novel intravesical formulation of imiquimod, a toll-like receptor agonist. … Continue reading

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Intravesical instillation of onabotulinum toxin A embedded in inert hydrogel in the treatment of idiopathic overactive bladder: A double-blind randomized pilot study.

Scand J Urol. 2016 Jun;50(3):200-5. Krhut J1, Navratilova M2, Sykora R1, Jurakova M2, Gärtner M2, Mika D1, Pavliska L3, Zvara P4. 1 Department of Urology , University Hospital , Ostrava , Czech Republic 2 Department of Obstetrics and Gynecology , University Hospital , … Continue reading

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A Phase 2 Study of Vesimune®, intravesical imiquimod, for the Treatment of Carcinoma in Situ Bladder Cancer

AUA poster presentation, Saturday, May 7, 2016 10:30 AM-11:30 AM A Phase 2 Study of Vesimune®, intravesical imiquimod, for the Treatment of Carcinoma in Situ Bladder Cancer Nicholas Donin*, Karim Chamie, Los Angeles, CA, Madhu Reddy, Philadelpia, PA, Dana Kivlin, … Continue reading

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The Chemoablative Effect of VesiGel® Instillation in Patients with NMIBC – Preliminary Results

AUA poster presentation, Saturday, May 7, 2016 8:00 AM-10:00 AM The Chemoablative Effect of VesiGel® Instillation in Patients with NMIBC – Preliminary Results Boris Friedman*, Yoram Dekel, Haifa, Israel, Andrea Tubaro, Rome, Italy, Ami Sidi, Benjamin Shalva, Holon, Israel, Jack Baniel, … Continue reading

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Preclinical trial of serial MitoGel® instillations into the pelvicalyceal system of the Yorkshire swine

AUA poster presentation, Saturday, May 7, 2016 8:00 AM-10:00 AM Preclinical trial of serial MitoGel® instillations into the pelvicalyceal system of the Yorkshire swine Nicholas Donin*, Sandra Duarte, Los Angeles, CA, Dalit Strauss-Ayali, Yael Agmon-Gerstein, Nadav Malchi, Ra’anana, Israel, Allan … Continue reading

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